Firstly, I wholeheartedly agree that safeguards and ethical guidelines are necessary when it comes to implementing these kinds of systems. It's essential that we consider the potential risks involved in using autonomous AI agents for various tasks, especially if they have access to sensitive data or can impact human lives directly.

And I would like to present some contra ideas regarding the idea that these agents could become uncontrollable or behave unpredictably. While there certainly is a risk associated with advanced machine learning algorithms developing beyond their initial programming parameters - which could lead them towards unpredictable behavior - isn't this true for any type of computer program? The difference here lies mostly within how we approach testing and monitoring an agent's decision-making processes as opposed to other types of software development practices.

Furthermore, while you discussed examples such as self-driving cars prioritizing passenger safety over pedestrians' safety being concerning from an ethical perspective; don't you think it might also be possible for such vehicles not programmed by humans but rather trained through neural networks will prioritize pedestrian safety instead due precisely because one thing they do better than us humans is recognizing patterns?

Overall though, thank you again for discussing this important issue so thoroughly – discussion about ethics surrounding emerging technologies should never end!